Jean-Michel Claverie is full professor of Genomics and Bioinformatics at the School of Medicine of Aix-Marseille University, director of the Mediterranean Institute of Microbiology, and head of the Structural and Genomic Information Laboratory, a unit of the French National Research Center (CNRS) that he founded in 1996. He got his initial training both in biochemistry, computer science and theoretical particle physics at the University of Paris and combined his multidisciplinary education into a Doctorate (Dr. Sc.) on the subject of mathematical modeling of biological system in 1977. He then successively hold research positions at the Jacques Monod Institute (CNRS) in Paris, then at the Salk Institute in La Jolla, before creating in 1982 one of the first pre-Internet era computational biology laboratory at the Pasteur Institute (Paris) where he remained until 1990. He then returned to the USA, at the National Center for Biotechnology Information (NCBI, NLM-NIH, Bethesda) where he participated to the exciting beginning of the genomic era, as a NIH senior Fogarty scientist, until 1995. Before returning to France, he spent one year as director of bioinformatics at Incyte pharmaceuticals (Palo Alto). Owing to his theoretical background, Jean-Michel Claverie worked on a wide range of topics ranging from the mathematical modeling of ultracentrifugation experiments, microbial and human genetics, cellular immunology, and more recently microbial genomics. Following the discovery and initial characterization of Mimivirus, the first "giant" virus in 2003, he then focused on the search for more giant and/or unconventional viruses in increasingly exotic environments. In the last ten years, his laboratory described four new families encompassing the largest known viruses in terms of particle and genome sizes: the Mega/Mimiviridae, the Pandoraviruses, Pithovirus and Mollivirus. The last two viruses were revived from 30,000 year-old Siberian permafrost, opening the field of "Paleovirology". While continuously searching for more ancient and/or exotic viruses, his laboratory is also involved in deciphering the biology and evolutionary origin of these giant viruses. The laboratory’s approaches include structural, molecular, and cellular biology, high throughput proteomics, genome and transcriptome sequencing, environmental sampling, large-scale comparative genomics and metagenomics, together with the development of relevant bioinformatics methods for sequence analysis and data mining. Dr. Jean-Michel Claverie (H index=66) co-authored more than 240 scientific publications that gathered more than 17,000 citations, as well as the best-seller book "Bioinformatics for Dummies". He was a member of the Board of reviewing editors of Science for 10 years (2002-2012). He was recipient of the CNRS Silver medal in 2003, and became a Knight in the National Order of the Academic Palms in 2016. He is a member of the 2018 Clarivate analytics list of highly cited researchers. He will be forced into mandatory retirement (French regulation!) in sept 2019, and is actively looking for a new research position that will allow him to continue his work on giant viruses, their origin, and their evolution. • EDUCATION 1977 Dr. Sc. "Mathematical modelling and simulation of biological systems", Institut Jacques Monod, University Paris 7, France 1972 Master (DEA) in Biochemistry, University Paris 7, Paris, France 1973 Master (DEA) in Applied Computer Science, Univ. Paris 6, Paris, France 1974 Master (DEA) in Theoretical Physics, University Paris 6 & 7 & 11, Paris, France •CURRENT POSITION(S) 2004 – 2018 Professor of Medicine (PU/PH), Biostatistics and Genomics, Aix-Marseille Univ. & APHM 2008 – 2018 Head, Mediterranean Institute of Microbiology (CNRS-AMU), France 1995 – today Founder & head, Structural & Genomic Information Lab. (CNRS-AMU), Marseille, France • PREVIOUS POSITIONS 1996 – 2004 Senior CNRS researchers (Director level 1) 1990 – 1995 Senior Fogarty visiting Scientist, NCBI-National Institutes of Health, Bethesda, USA 1982 – 1992 Head of laboratory (Computational Biology), Institut Pasteur, Paris, France 1989 – 1990 Professor of Immunology, Rouen University, Rouen, France 1975 – 1995 CNRS researcher (from junior to director grade, with on leave periods when abroad).

Kitaplar

Bioinformatics For Dummies

0

İleri