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Şizofreni & Dopamin hipotezi
The reasons why these drugs are effective on psychotic symptoms has been the subject of much research but remains controversial. However, all those that are effective have an action on dopamine, although individual drugs also affect other chemicals in the brain. Dopamine produces noradrenaline and in turn adrenaline—it forms part of a “stress pathway,” and we tend to describe it as this to people who wish to know. From its effect on reducing relapse, it seems reasonable that it is “buffering” individuals against stress or whatever it is that precipitates relapse. When medication has sedative effects, it can also assist with sleep and anxiety. So, a simple explanation might be: “We’re not sure exactly why these drugs are effective. But they all seem to act on a chemical called dopamine, which forms part of a ‘stress pathway.’ They seem to ‘buffer’ against stress and can assist with sleep and anxiety and also voices and disturbing beliefs.”
Sayfa 86 - Stresi azaltarak semtomlarda etkili gibi gözüküyor
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