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Size Matters
Our human tumors, it turns out, are remarkably similar to those of the animals with whom we live: our pet dogs. Dog cancer cells and human cancer cells are nearly indistinguishable. Dogs live longer than mice, so researchers can observe the cancer—and the treatments—over the long term. And, unlike most lab mice, pet dogs’ immune systems are intact, allowing oncologists to study how a cancer acts when challenged by natural defenses. Dogs are also simply much bigger than mice. This has implications, both practical—the tumors are physically easier to see—and philosophical (think of Peto’s paradox).
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