Denis Noble

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Denis Noble Quotes

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The logic for explaining the success of a gene does not lie in its DNA code; it lies in how that code is interpreted and in how the results of that interpretation fit into the overall successful logic of life.
A living cell is a continuing, action-packed drama. Molecules interact and change. One change triggers another, and so on and on. Complex chains of molecular interaction happen again and again. We call them 'pathways'. ... And proteins form the backbone of all these biochemical pathways.
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...the original question in genetics was not what makes a protein but rather 'what makes a dog a dog, a man a man'. It is the phenotype that stands in need of explanation. It is not just a soup of proteins.
Metaphor invention is an art not a science and, as with other art forms, the artist is nit necessarily the best interpreter.
The book is organised into ten chapters. Each uses a different musical metaphor for some aspect of the biology of life.
...the genome as a database for transmission of successful organism, rather than a program that 'creates' them. ...replace the metaphor of the 'selfish gene' by 'genes as prisoners'.
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