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If a blind person passed her finger repeatedly over the bumps of Braille, but had no motivation to learn it, no rewiring would occur, because the right neuromodulators would not be present.
The differences between a baby and an adult are easy to see, but the neural transition from one to the other does not happen in a smooth line. Instead, it is like a door that swings closed. Once it shuts, large-scale change is over.