The human genome consists of 3.3 billion base pairs. In 2003, when the Human Genome Project came to an end, it would have taken more than ten years to unravel the genetic code of a particular individual. Today our laboratory can process a trillion base pairs every day. The throughput of these machines has increased by a factor of 100 million over the past fifteen years: currently, one sequencer can decode an extraordinary 300 human genomes in a single day.